In this paper catalytic vinylation of morpholine with the acetylene at atmospheric pressure with formation of N-vinylmorpholine has been investigated. The influence of nature of catalysts and solvents on vinylation of morpholine in homogeneous conditions is studied. DMSO is chosen as optimal solvent and the effect of temperature influence and amount of catalyst for the vinylation process are investigated. Role of high-basic system KOH/DMSO and its nucleophilic interaction with acetylene has been shown and kinetics of morpholine vinylation is investigated. Heterogeneous catalytic vinylation of morpholine with acetylene in presence of catalysts KOH/AC-L and nanostructural KOH/activated coal has been investigated. Nanostructured KOH/activated coal catalyst proves more effective in the formation of Nvinylmorpholine.