Aim The purpose of the present research was to assess the knowledge as well as preference related to material of choice amongst various dental practitioners between titanium and zirconia. Methodology The cross-sectional study was conducted where a set of questions was designed by the research group to form a questionnaire that covers the knowledge of the participants and their preferred material in various scenarios. The questionnaires were distributed online, electronically using Google forms to the dental practitioners and dental students. Dental students, interns, general practitioners, post-graduate students, specialists and consultants were included in the sample of this study. Statistical analysis was conducted where comparisons between the various groups were done utilizing the Chi-square test.