Abstract Background: Men's most prevalent noncutaneous cancer is prostate. It causes 10% of male cancer deaths. The American Cancer Society predicts 186330 new prostate cancer cases and 26000 deaths in 2008. Prostate cancer rarely affects men under 40 or 50. Post-mortem autopsies may detect prostate cancer. Clinical cancer is rarer than latent or postmortem cancer. 80-year-olds may be 80%. Prostate cancer diagnosis and therapy evolve. Methods: From May, 2021 to April, 2022, researchers probed potential future events. In order to enroll patients in the study, all patients over the age of 55 who reported to the, at the Department of Radiology, Kamineni Academy of Medical Sciences and Research Centre (KAMSRC), Hyderabad, abnormal digital rectal examination, PSA, 4 ng/ml were assessed. Results: Laterally oriented base and midgland bilateral cores enhanced cancer detection from 80% to 96% compared to standard sextant. Different strategies have been implemented in an attempt to increase the TRUS biopsy detection rate. Neovascular assessment in prostate cancer patients using power Doppler ultrasonography is also provided. Conclusion: Doppler-targeted biopsy techniques have been shown in a large number of trials to significantly improve cancer detection rates. In order to gain an idea of how people in India feel about Doppler-directed targeted biopsy techniques, we chose to look into how well power Doppler ultrasonography can spot prostate cancer.