BACKGROUND - Fungal infections of the central nervous system, especially cerebral mucormycosis are rare. Usually, it is a secondary opportunistic infection than a primary infection of the brain. Recently there has been a rise in cerebral mucormycosis in the patients of COVID 19 due to various factors like impairment of barrier defense mechanisms and use of immunosuppressive medications like steroids for the treatment of COVID 19. The following observational study is conducted by the neurosurgery unit of the General surgery department at Gandhi Medical College Bhopal and its associated hospital. AIMS AND OBJECTIVES – The aim of this study was to determine the pattern of cerebral involvement of mucormycosis and the various associated factors in the patients of COVID 19 infection. MATERIALAND METHODS- This is an observational study conducted by the neurosurgery unit of the General surgery department of Gandhi medical college and associated Hamidia hospital Bhopal. Details of 55 patients who were treated in various departments of this hospital for post-COVID 19 mucormycosis infection with any kind of cerebral involvement are collected and analysed. The study was undertaken for the duration of 08 months from March 2021 to October 2021.