Introduction- Teaching embryology in particular cardiovascular system (CVS) is challenging one with didactic lectures. Multiple modes of teaching by videos, using embryology models and making models by play dough facilitate the better understanding and retention of subject. Aims/objectives- To make the students understand various developmental stages of CVS clearly and retain that knowledge. Methodology- The development of CVS was taught by using videos, embryology models and making models by play dough to total of 75 students which were divided into small group of 25, after the class feedback was taken by the students to assess which method is better for teaching embryology of CVS. Results and Discussion- 50(66.7%) students opined that play dough models were helpful in understanding the developmental stages clearly with significant P value=0.038*. 74(98.7%) students found this method of teaching with play dough interesting with significant P value <0.001*. Conclusion-Play dough models can be used to teach small groups about development of CVS effectively