Background: Plantar fasciitis is one of the most common causes of heel pain. This prospective study compared the efficacy of local injection of corticosteroids vs platelet-rich plasma (PRP) in the treatment of plantar fasciitis. Methods: Patients were randomly allocated into 2 groups of Corticosteroid (Group A) and PRP (Group B) with 38 and 37 patients respectively. Patients were treated with local corticosteroid (cs) injection in group A and autologous PRP injection in group B. Clinical assessment was done prior to the injection and at 1, 3, 6 and 12 months following the injection, which included visual analog pain scale, subjective rating using the modified Roles and Maudsley score, functional outcome score by the American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hind foot scale. The mean age, sex, and body mass index of both groups were comparable. Results: Post-injection we found that both PRP and CS significantly improved VAS, R&M, and AOFAS scores compared to the pre-injection condition. In addition, CS has better pain relief and improved function in the short term (within the first month) compared to PRP; however, PRP has better pain relief and improved function in the long term (after 6 months) compared to the CS group. Conclusion: The observations made in the present study suggest that the treatment of plantar fasciitis with steroid or PRP showed no significant difference at 12 months of follow up but corticosteroid showed better results in the short term (1-3 month), whereas PRP was found to be better in the long term follow up (6 months).