Abstract: Phytochemicals represent traditional knowledge of compounds effective in symptomatic relief and potential healing properties. The idea has emerged from the fact that natural resources such as neem, turmeric, cloves etc. have been used to cure health problems since a really long time. Even in the current modern world, people have more preference towards natural therapeutics than modern drug formulations. Antibiotics are the drugs which are most easily prescribed unnecessarily to attain extremely rapid symptomatic relief. The practice has led to natural selection of resistant bacterial strains which are spreading at an alarming rate. The world without antibiotics is horrible to contemplate and can cause uncontrollable mortality rate in future due to resistant bacterial infections. The review elaborates importance of phytochemicals as compounds of natural origin, easy production, industrialization scope, broad spectrum antibacterial capabilities to tackle the crisis of antibiotics in the ever growing era of multi drug resistance