Varunadi kwatha(Kashaya), Chandraprabha vati and Gokshuradi guggulu preparation is a Herbo-mineral formulation mentioned in Sharangadhara Samhita and Bhaishajyaratnawali for the Chikitsa of Muthravahastroto vikaras. Authentication was done before the pharmacological analytical study of this drug. The finished product was subjected for necessary analytical parameters. Present work was carried out to standardize the finished product of Varunadi kwath(Kashaya), Chandraprabha vati and gokshuradi guggulu preparation in terms of its identity, quality and purity. Pharmacognostical and Physico-chemical observations revealed all the specific characters of active constituents in the preparation. The data obtained could be useful in deciding the standards for this potential ayurvedic drug and can contribute in the uses and preparation of quality ayurvedic drugs. The same drugs were used for OPD practiced to rule out the efficacy. The resultant effects noted was positive and the symptoms were managed efficiently and also the patient feedback regarding the treatment protocol was good. This gives further motivation to prepare the medications by our own to achieve desired therapeutic efficacy with hundred percent genuine qualities.