Abstract: The safe and effective management of Pharmaceutical waste has received a lot of attention due to its direct relation with human health and environment. The Knowledge of how to dispose unused medications is similarly significant like medication utilization. Numerous Pharmaceutical compounds at consideration level have been accounted for Wastewater. The revelation of an assortment of pharmaceuticals in surface, subsurface and drinking waters across the nation is increasing worries about the possibly unfriendly ecological results of these contaminants. In spite of the fact that an innovation and treatment convention as of now exists, effective Pharmaceutical waste management still stays a significant issue for all health care facilities. This article reviews the background of Pharmaceutical wastes, its impact on the environment and human health. This Review paper could give the significance of the legitimate removal of Pharmaceutical waste.