Objective: To determine the effects of preoperative probiotic or synbiotic treatment on patients having abdominal surgery's postoperative results. Methods: Between 2019 and December 2022, patients over 70 years old who are having a laparoscopic colon resection at our unit will participate in this prospective, double-blind, randomised trial. Following the signing of an informed permission, all patients were enrolled. The patients were divided into Group A (antibiotic + probiotic), Group B (antibiotic + synbiotic), Group C (antibiotic + placebo), or Group A (antibiotic + synbiotic). Results: Ten patients (5 men) made up Group A; eight patients (4 men) made up Group B; and ten patients (6 men) made up Group C. Each group had one patient who developed a postoperative problem that was treated conservatively