Background: Rheumatoid arthritis in children and their families can be a significant health burden. They're linked to the risk of physical impairment, a lower quality of life, and a lot of direct and indirect expenditures. The goal of this study is to characterise the clinical spectrum of Juvenile Idiopathic Arthritis (JIA) in children at Zagazig University hospitals, as well as the frequencies and various patterns of JIA. Patients and methods: A cross-sectional research comprised 120 patients with an average age of 16 years. From December 2017 to December 2019, data on juvenile idiopathic arthritis was gathered during a twoyear period. Complete blood count, reactive protein, ANA, RF, C3&C4, creatine phosphokinase, and EMG were all performed. Management and treatment strategies were implemented, and data on the outcomes was gathered. Results:Females account for the majority of our rheumatological illness patients.In our analysis, JIA was the most frequent rheumatological illness, followed by SLE and lastly HSP.In our study, oligoarticular JIA was the most prevalent subtype of JIA, followed by polyarticular and then systemic onset type.SLE is the second most prevalent illness in our research, with the majority of patients being women.The majority of individuals had cutaneous symptoms and a fever.The most commonly utilised drugs were corticosteroids, cyclophosphamide, and mycophenolate mofetil.HSP was the most prevalent kind of vasculitis found in our research.The majority of patients are females, and those with severe GI symptoms and nephritis got corticosteroids. Conclusion: The prevalence of rheumatological disorders in children is underestimated, and there is a lot of overlap in diagnosis. Because paediatric onset is less apparent than adult start, some patients have a significant diagnostic lag. Early identification and proper care of these children is critical for them to have a normal or near-normal life, particularly in patients with rheumatological illnesses that cause chronic morbidity, such as JIA.