ABSTRACT This study aimed to determine the nursing organizational factors and patient safety in selected healthcare facilities in the Philippines. It utilized quantitative approach of research specifically descriptive correlational research design. The inclusion criteria of the entire population were composed mainly of 455 nurses employed among the five selected healthcare facilities in Caraga Region, Philippines within a period of 1 year and above offering inpatient and outpatient healthcare services. Results revealed that there was a positive response on organizational factors such as nurse participation in hospital affairs, nursing foundations for quality care, nurse manager leadership, ability and support and collegial nurse-physician relationships. Patient Safety with regards to wok area/unit, supervisor/manager, communications, and frequency of events reported, patient safety grade, hospital and number of events reported were positively performed and practiced. The patient safety practices were directly affected by the organizational factors being tested.