Induction of labour is an obstetric procedure designed to pre-empt the natural process of labour by initiating its onset artificially before this occurs spontaneously. The ultimate weapon at the disposal of the obstetrician is intervention to deliver the baby. This can be done by Induction or caesarean section. His decision to take thestep relies on assessment of the “Obstetric balance”. The present study is a comparative study between oral prostaglandin E2 (PGE2) and intravenous oxytocin (IV oxytocin) for induction of labour carried out at Hospital.One hundred and twenty consecutive patients stated for induction of labour satisfying the selection criteria for the study were alternately recruited to Prostaglandin or oxytocin groups. The maternal side effects were more in the prostaglandin group.One occurrence of hypertonic uterine action a case of premature rupture of membranes in the PGE2 group. Post-partum hemorrhage was observed in 2 of the 43 patients of oral PGE2 and in 6 of the 45 patients induced with oxytocin.