Effective pain management is critical for women after caesarean delivery, and significant postoperative pain is related with persistent pain, higher opioid use, delayed functional recovery, and postpartum depression. Intrathecal morphine is the standard method for post-c-section pain, offering superior and extended analgesia. Scheduled non-steroidal anti-inflammatory medications and acetaminophen should be included in multimodal analgesia, with opioids reserved for severe breakthrough pain. Wound infiltration and transversus abdominis plane blocks are critical components of multimodal analgesia for patients who cannot receive neuraxial opioids or who do not have appropriate pain management. While analgesics may transfer to breastfeeding infants, transfer could be reduced by careful drug selection and administration timing.