SUMMARY. In total 60 children were examined, over 22 of mature newborns are born from healthy parents , 20 newborns are born from mothers with OPG-gestosis, and 18 newborns born from mothers with OPG-gestosis combined in chronic pyelonephritis . It was identified that in children with complicated course of disease, inheritability was rarely aggravated, the disease was followed by epiphenomenon , in the main group of newborns were observed a low level of of glomerular filtration, tubular reabsorption of acidogenesis, which were associated by a disproportion of the phospholipid spectrum of erythrocyte membranes due to the increased blood activity and LPO.