This work aimed to analyze professional morbidity in the coal industry of Uzbekistan. The method of data copying from outpatient cards of professional patients and its statistical processing was used for analysis. The professional morbidity rate in the coal industry was 108 cases per 10 thousand workers and 6.8 times higher than in other industries. At surface coal mining in the open pit, as compared to underground mining in a coal mine, the number of cases of first detected occupational diseases was, on average, 2.6 times lower. Thus, the vibratory disease was most frequently met among workers of open-cast mining in comparison with underground mining 1.4 times, and professional bronchitis, bronchial asthma and pneumoconiosis - among workers of underground mining in comparison with open-cast mining in 2.3 times.Vibration disease is diagnosed among workers of underground mines at the work experience of 16 years, while among workers engaged in open-cast coal mining - 21 years and more. The analysis of results of medical and labor examination with professional diseases of coal industry workers showed that among 48.3 ‰ of workers, there were 30.4 ‰ disabilities of Group III and 17.8 ‰ disabilities of Group II. These indicators had differences depending on the brand of coal mined, so in the mining of brown coal (SiO2-10%), the disability of professional genesis amounted to Group II 7.5 ‰ and Group III 31.3 ‰, while in the mining of coal (SiO2-4%) 4.4 times more established Group II disability (73.3 ‰ workers) than Group III - (16.7 ‰). Conclusion: Coal dust of hard and lignite differ in chemical and physical properties and degree of dispersion, which affects the level of occupational morbidity and disability of workers.