Post-traumatic spine immobilization plays an important role in the prevention of spinal cord injury. The splints are used today by the emergency department to immobilize the spine include a backboard and a immobilizer vest. A backboard bed usually is used for those injured in the open environment and a immobilizer vest, commonly is used for those injured in enclosed spaces such as a car. This study aims to design and manufacture a new spine immobilizer vest (NSIV) with features such as being lightweight and low volume, disposable and hygienic, very low cost, recyclability and the ability to be fitted in all emergency centers for replacing the old immobilizer vest. The design and construction of the NSIV was done in two stages. In the first step, with the help of measures obtained from measuring different people, the design and fabrication of prototype lattice polypropylene sheets were successfully designed and manufactured, and after the test on it, the necessary corrections were done. In the second step, the dimensions of the prototype were completed and were designed computerized and accurate with the help of AutoCAD software and precise cut molding was also made that was used to produce new spinal immobilizer vest (NSIV).