Online ISSN: 2515-8260

NEUROPROTECTIVE EFFECTS OF OIL OF COCOS NUCIFERA ON ALUMINIUM CHLORIDE-INDUCED BRAIN DYSFUNCTION IN RATS.

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Bhaskar B. Gavitre1,2,

Abstract

This study examined the neuroprotective effects of fractions- BMCT (Best Medium Chain Triglycerides) AMCT (All Medium Chain Triglycerides) and WCO (Whole Coconut Oil) of Cocos nucifera on the learning and memory in aluminium chloride induced brain dysfunction in rats. All Wistar rats of groups II to VI were received respective treatment doses (100/200 mg/kg) 30 minutes before oral administration of Aluminium chloride (100 mg/kg), daily for 42 days. On day 20, 21 and 42 following the start of aluminium chloride administration rats were subjected to evaluation of gross behavioral activity using Open field arena (OFA). Behavioral score recorded usingLine Crossing, Center Square Entries, Rearing and Grooming.

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