Abstract: Mucormycosis is a rare angio invasive infection mainly recognized in immunocompromised patients which occurs due to the fungi mucorales. This rare fungal infection can be classified into rhino-orbitocerebral, cutaneous, disseminated, gastrointestinal, and pulmonary types. Inspiote of aggressive treatment once detected or diagnosed overall increased mortality rate is reported. This review aims in providing with brief details regarding the Etiopathogenesis of Mucormycosis, fatality of rhinocerebral Mucormycosis along with recent advances in diagnostic and treatment methods.