Introduction: Many foramina and fissures are located in the sphenoid bone that carries nerve and blood vessels of the head and neck. Sphenoid bone is an unpaired centrally situated bone. In the cranium it lies anteriorly and to the middle cranial fossa its contribution is large. Also contributes to the posterolateral wall of the orbit and the lateral wall of the skull. Foramen spinosum is a very small foramina situated at the edge of the sphenoid bone in the middle cranial fossa. In the greater wing of the sphenoid bone foramen of spinosum is one of two foramina present. The foramen rotundum is a circular opening in the sphenoid bone that connects the pterygopalatine fossa. The foramen rotundum is a spherical opening positioned in the floor of the skull.