Abstract: The article presents the methods of selection of parental forms, the use of different selection methods as analytical selection, transgressive selection, convergent selection and their effectiveness for creating new competitive varieties of cotton. Efficiency of application in hybridization of wild and ruderal forms as well as local and foreign cotton varieties in creation of new high-ripening and fork-resistant cotton varieties and lines with improved valuable morphological features. It has been revealed that analytical selection depending on the selection method allows to create new high-ripening, vilt-resistant, highyielding varieties of cotton, transgressive selection depends on the geographical origin of initial forms and the greatest success in transgressive selection is achieved at return or saturated crosses. Convergent selection method is the most perspective direction in creation of vilt-resistant, early maturing, highly productive varieties and lines that will have the best features of both parental forms. In the process of selection work on the method of analytical selection created a variety of cotton Omad, which was introduced in the State Register in 1999 and zoned by Samarkand region, by the method of convergent selection created a variety of cotton C-8294 (Gurlen), which was introduced in the State Register in 2020 and zoned by Kharezm region.