Online ISSN: 2515-8260

MATERNAL AND PERINATAL OUTCOME OF PREGNANCIES WITH TERM LABOUR AND MECONIUM STAINED AMNIOTIC FLUID – HOSPITAL BASED PROSPECTIVE OBSERVATIONAL STUDY

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Dr. Neha Khanam1 , Dr. Kalpana Verma2 , Dr. Usha Singh3 , Dr. Kalpna Kulshresthra4 , Dr. Nahid Khanam5

Abstract

Fetal passage of meconium cause MSAF (Meconium Stained Amniotic Fluid) which complicates about 7%-20% of all pregnancies worldwide, the incidence being higher in blacks and South Asian ethnicity. Rarely meconium passage occur before 34 weeks of gestation and then incidence increase beyond 37 weeks of gestation. As the gestational age increases towards post term incidence of cesarean section also increases with reported frequencies at 37, 40 and >42weeks being 3%, 13% and 18% respectively. The risk factors for meconium stained amniotic fluid are consists of both maternal and fetal. The maternal factors are maternal chronic respiratory or cardiovascular disease, hypertension, gestational Diabetes mellitus, preeclampsia, eclampsia, post term pregnancy. The Fetal factors consists of oligohydramnios, intrauterine growth restriction, and poor biophysical profile. Objective:  To study the maternal outcome in Pregnancy in control group and study group i.e. term labour with meconium stained amniotic fluid.  To study the perinatal outcome in control group and study group. The Present study was conducted in department of Obstetrics and Gynaecology after taking approval from Institutional Ethical committee and informed consent from patient in SIMS HAPUR. Sample Size: 200 cases Group A (100 cases): Pregnant women With MSAF (Meconiumstained Amniotic Fluid) Group B (100 cases): Pregnant women with clear liquor. Selection of subject: Period of study- November 2020 to October 2022. Study Design: Hospital based Prospective Observational study Result:  It was observed that majority of the patients were in the age group of 21-30 years in both the groups i.e. 82% in study group and 73% in control group.  Chorioamnionitis seen in 8% in study group compared to 3% in control group.  Study shows meconium group was two times more likely to undergo caesarean section (53%) compared to the non-stained fluid group (25%).  Present study showed that NICU care needed more in MSAF group babies (26%) than that of control group (4%).  In the study it was found that meconium stained liquor associated with poor perinatal outcomes. 11% in study group versus 2% in control group developed neonatal sepsis. Conclusion: Conclusion of the current study explained that maternal and perinatal outcome are compromised. Cesarean section rate, chorioamnionitis, puerperal sepsis, low Apgar score, NICU admissions, fetal hypoxia and perinatal mortality were significantly higher in meconium stained amniotic fluid and non-reactive NST.

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