Online ISSN: 2515-8260

Maternal and Perinatal Outcome in Intrahepatic Cholestasis of Pregnancy

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Dr. Anandjit Kaur1 , Dr. Reena Sood 2 , Dr. Sangeeta Pahwa3 , Dr. Harmandeep Kaur4

Abstract

Background : Intrahepatic cholestasis of pregnancy (ICP) is a multifactorial condition of pregnancy characterised by pruritis in the absence of a skin rash ,with , raised bile acids, and/or abnormal liver function tests neither of which has an alternative cause and both of which resolve after delivery. We in the current study tried to evaluate maternal and perinatal outcomes in cases and controls in obstetrics department presenting at our hospital . Methods: Antenatal patients complaining of unexplained pruritis without rash, with raised bile acids and/or abnormal LFTs were included in our prospective one year case-control study. There were 60 cases of ICP in our study and 60 controls . Maternal and perinatal outcomes were compared in both groups and statistical analysis was performed using chi-square test and fisher exact test . ‘p’ value < 0.05 was considered as statistically significant in this observational study .

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