Background: Leptomeningeal metastasis (LM) is a condition that develops when malignant cells from an extrameningeal primary tumor invade the leptomeninges. Patients with solid tumors (5- 8%) and patients with lymphohematopoietic neoplasms (5-15%) are both diagnosed with it. Among solid tumors, leptomeningeal metastases are most frequently caused by metastases to the breast and lungs. The management of the patient depends on the early detection of LM. Cerebrospinal fluid (CSF) cytological analysis is still essential for LM diagnosis. The molecular subtypes of breast cancer should affect LM propensity because they are correlated with tumor behavior and prognosis.