:Background: Levobupivacaine is a long acting, amide-type local anaesthetic that is the S(−) \3- isomer of the racemate bupivacaine. In general, in vitro, in vivo and human volunteer studies of nerve block indicate that levobupivacaine is as potent as bupivacaine and produces similar sensory and motor block. Dexmedetomidine is used as an adjuvant in spinal anesthesia and is associated with prolonged motor and sensory block, hemodynamic stability, and less requirement of rescue analgesia in 24 h as a result it facilitates reduction in dose of local anesthetic. Aim of the study: To compare isobaric levobupivacaine 0.5% versus isobaric levobupivacaine 0.5% with 3 mcg Dexmeditomidine in spinal anaesthesia. Materials and methods: The present study was conducted in the Department of Anesthesiology of the medical institution. For the study, we selected a total of 50 patients in the age group of 20-65 years of physical status American Society of Anesthesiologists (ASA) Classes I and II admitted for surgeries requiring spinal anesthesia. An informed written consent was obtained from all the participants after explaining them the protocol of the study. The patients were randomly grouped into two groups, Group 1 and Group 2. Group 1 patients received 3 ml (15 mg) of 0.5% isobaric levobupivacaine + 0.3 ml normal saline, whereas Group 2 patients received 3 ml (15 mg) of 0.5% isobaric levobupivacaine + 0.3 ml (3 μg) dexmedetomidine. Results: It was observed that the number of male patients in group 1 and 2 was 12 and 14, respectively. The number of female patients in group 1 and 2 was 13 and 11, respectively. The mean age of patients in group 1 was 46.28 years and in group 2 was 47.12 years. It was observed that the mean duration of sensory block in Group 2 was significantly higher than Group 1. The mean duration of motor block in both the groups was similar and was statistically nonsignificant. Conclusion: Within the limitations of the present study, it can be concluded that the duration of sensory block increases with addition of 3 mcg of dexmedetomidine with Levobupivacaine as compared to plain Levobupivacaine. The results were found to be statistically significant.