Online ISSN: 2515-8260

INFLUENCE OF SERUM MAGNESIUM LEVELS ON PRIMARY HYPERTENSIVE CASES AND ITS ASSOCIATION WITH CARDIOVASCULAR CHANGES AND RETINOPATHY

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1Ravi N Sangapur, 2Anusha N Sangapur

Abstract

Background: Hypertension is a growing concern in the Indian population with urbanization and developments in work culture and treatment methods. Aim and objective: To evaluate the influence of serum magnesium levels in gradations of primary hypertension and evaluate its impact on co-morbid conditions. Methods: Hypertensive patients were screened and included in the study by categorizing them in to grade I and II based on blood pressure levels. Socio-demographic, physical and systemic examination details were recorded with pre-designed questionnaire; electrolyte levels, fasting blood sugar, status of retina and heart were assessed and analyzed using t-test and logistic regression. Results:Total 100 patients in the study, mean age was 59.3±14.79 years; male predominance (61%); normal retina (83%) and presence of pre-diabetic conditions (67%) was observed, with normal serum magnesium levels in majority (76%). Serum magnesium levels were significantly associated with grade I (P = 0.0173) patients; influencing systolic and diastolic blood pressure values (r = -0.3552, P = 0.003; r = -0.2160, P = 0.0309, respectively). Conclusion:The optimal values can be further established by evaluation of large sample size, quality of life during treatment, and influence of co-morbidities/complications of hypertension, among others.

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