Annotation. It was proved that the studied new phytopreparation Lesbachol under experimental conditions exhibits a pronounced protective effect on the gastric mucosa. And so, under the influence of lesbachol, the area of ulceration decreases by 58.5%, and in the group of the studied drug to glycerol - by 32.7%. The results showed that lesbohol with small punctate ulcers compared with the control group was reduced 2.6 times, with large ulcers it was reduced 2.8 times, with striped ulcers 2.6 times, the total number of ulcers decreased 2.6 times ... Therefore, Lesbokhol, as a potential highly effective anti-ulcer agent, is of practical interest and can be recommended for the prevention and treatment of gastric ulcer and duodenal ulcer.