Abstract: As a result of research, it has been established that synthetic karate pyrethroid causes functional changes in antioxidant enzymes in microsomes and mitochondria. An important aspect of our study was the comparison of the taxation rate when animals were poisoned with a karate pesticide and when animals were protected from poisoning with an antioxidant of plant origin. The results obtained indicate that the plant antioxidant factor (PAF) has protective properties and accelerates the restoration of enzyme activity.