Abstract A total of 2105 patients with pulmonary tuberculosis were examined, of which 19.5% of patients were found to have concomitant pathology. It was found that in patients with concomitant pathologies, tuberculosis is severe, with severe symptoms of intoxication and respiratory manifestations. Isolation of MBT and the presence of drug resistance were higher in the group of patients with concomitant pathology. The presence of concomitant pathology adversely affects the clinical course of pulmonary tuberculosis.