Online ISSN: 2515-8260

IMPORTANCE OF SUPER DISINTEGRATING AGENTS IN FAST DISSOLVING TABLETS

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Kehar Singh, Dr. Gaikwad Dushyant Dadabhau, Satbir Singh

Abstract

Over the past few decades, there has been an increasing demand for oral disintegrating tablets, which are an emerging trend in innovative drug delivery systems. Solid dose forms are made more effective by the use of super disintegrants. This is accomplished by lowering the disintegration time, which raises the pace at which drugs dissolve. Disintegrants are compounds or mixtures of substances that are added to the medicine formulation to help the content of tablets or capsules break up or disintegrate into tiny particles that dissolve more quickly than they would if disintegrants weren't present. Superdisintegrants, a class of more modern agents, have been developed in recent years. Super disintegrants fall into a variety of categories, including natural, co processed, synthetic, and semi-synthetic mixes, have been used to create effective mouth-dispersing tablets and get beyond the restrictions of traditional tablet dose forms. Super disintegrants are often employed in solid dosage form at modest levels, approximately 1–10% by weight in relation to the dosage unit's total weight. This study includes all the information available on super disintegrants, such as their types, mechanisms, selection criteria, optimal features, incorporation techniques, and advantages. These super disintegrants are employed in formulations to give safer, more effective drug delivery while maintaining patient compliance.

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