Renal failure as the initial presenting manifestation of acute lymphoblastic leukaemia (ALL) is uncommon. In acute leukaemia, commonly occurring renal complications are due to treatmentrelated side effects such as tumour lysis syndrome, use of nephrotoxic drugs and sepsis. [1] Here, we are presenting an interesting case of 40 years old lady with non-oliguric acute kidney injury (AKI) of no apparent cause and vague abdominal pain. Investigations revealed anaemia, thrombocytopenia with mild leucocytosis & few abnormal lymphoid cells on peripheral blood smear, deranged renal functions with high uric acid level.Subsequently bone marrow biopsies & Immunophenotyping revealed diagnosis of Tcell ALL.