ABSTRACT: Exponential development into ICT and Web technology has had significant effect upon business & infrastructure distribution structures of the current global economy. Electronic -Hospital Management Systems (EHMS) offer benefits of streamlined procedures, efficient compliance & tracking, quality patient service, strict cost containment and expanded efficiency. Healthcare Insurance Portability & Accountability Act ( HIPAA) provisions, that have established standard of healthcare sector in management of medical reports as well as protection of patient details. The research focused on identifying success metrics for Hospital Information Systems (HIS), summing up current widely accepted guidelines & procedures such as Health Level Seven (HL7) requirements for shared communications communication, HIS elements, etc. For several customized variants of E-HMS Systems & HIS upon marketplace, a basic module edition of E-HMS was meant to offer simple understanding to analysts and business specialists. Throughout numerous positive research articles discussed in the study, the performance indicators & difficulties presented through positive adoption of E-HMS have been highlighted.