Hemolytic specimens are common in laboratory practise, accounting for approximately 3% of all samples referred to a clinical lab .It can have an impact on the results of analytes like AST, LDH, potassium, and sodium. High glucose levels have been shown to interfere with Jaffe creatinine assays in peritoneal dialysate, as well as creatinine, calcium, albumin, chloride, and FT4 levels in serum . Diabetes, a rapidly growing chronic disease characterised by hyperglycemia, has a 9.8percent prevalence in our state. As a result, the likelihood of glucose acting as an interference factor is relatively high..