Furosemide, a commonly used diuretic, presents difficulties due to its solubility and effectiveness, requiring creative administration methods. Olibanum mucilage, obtained from Boswellia trees, has mucoadhesive and film-forming characteristics that are suitable for medicinal uses. The study included extracting mucilage from Olibanum obtained from Boswelliaserrata using a maceration procedure with water and chloroform. The mucilage was then precipitated using 100% ethanol, resulting in a yield of 40% w/w. Mucilage was used in varying percentages of 5%, 7%, and 10% w/v. The granules were produced using the wet granulation method. The granules were assessed for fines percentage, average particle size, total porosity, compressibility index, and flow characteristics. The qualities were compared with starch, which served as the standard binder at a concentration of 10% w/v. The tablets were formulated and assessed for consistency in content, hardness, fragility, disintegration time, and dissolving behavior in a laboratory setting. Therefore, 5% and 7% concentrations are optimal for preparing Furosemide tablets.