Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is an important cause of liver disease in India. Epidemiological studies suggest its prevalence in around 9% to 32% of general Indian population, but with a higher prevalence in those having overweight / obesity and diabetes. Present study aimed to investigate the usefulness of ‘Fatty Liver Index’ an algorithm to predict the presence of Non Alcoholic Fatty Liver Disease among the Population visiting the Master Health Check-up of a tertiary care centre. Material & Method: The present cross sectional diagnostic study was conducted among the patients more than 18yrs with fatty liver diagnosed by USG visiting the master health check-up of AVMC & H. After obtaining informed and written consent from the patients, detailed history, anthropometric measurements, clinical assessments and laboratory investigations were done. The predictors of Fatty Liver are obtained and the FLI calculated based on the formula and USG Abdomen done to correlate the prediction. All data were collected by the investigator and was analysed statistically to find the level of significance of the study.