Knowing the causes of burnout syndrome and finding solutions in this direction is essential.For this reason, this research aims to determine sports and health sciences students'burnout levels and to examine the causes of burnout syndrome. In addition, it is aimed to reveal whether the burnout levels of sports and health sciences students differ according to faculties and departments. A mixed design was used in the research method. The sample group was reached for the quantitative research design with easy sampling. The study sample consisted of the students of the faculty of sports sciences and the faculty of health sciences. For the qualitative design, students with high burnout were reached using the purposive sampling method. Maslach Burnout Inventory-Student Form for quantitative data and semi-structured interview form for qualitative data were used as data collection tools. Quantitative data obtained were analyzed using Independent Groups t-test and One-way Analysis of Variance, and qualitative data were analyzed using thematic analysis. As a result of the quantitative findings, a statistically significant difference was found between the burnout, exhaustion, and depersonalization levels of the students of the faculty of sports sciences and health sciences. It has been revealed that physiotherapy and rehabilitation, and nursing students have higher burnout, exhaustion, and depersonalization levels than the faculty of sports sciences. No significant difference was found in the competence subdimension. As a result of the qualitative findings, the data were collected under three themes: cognitive - problems caused by teaching programs, emotional-psychological effects, and physical-physiological effects. In this research, the participants strive towards a goal. Participants are in a state of expectation in return for their performance. However, their expectations are not met at the expected level. This situation causes students to experience stress and emotional reactions for a long time. As a result, this leads to exhaustion and depersonalization.