Abstract SICANTIK is an electronic information system created to prevent maternal and child deaths. In 2017, 30 out of 36,313 women died of maternal causesin Sidoarjo Regency. The overall mortality rate was83 deaths per 100,000 live births. This study aims to analyze the effectivenessof SICANTIK utilization by the community health centerofficers asan effort to improve maternal and child health. SICANTIK information system was evaluated using Human, Organization, andTechnology-FitFramework(HOTFit Framework) concerninghuman factors. The evaluation wasdoneintwo weeks at four community health centers. The evaluation of SICANTIK health information systemutilization demonstrated thatthe users were midwife coordinatorson the age range of 30-40 years and have worked for more thanthree years. The user satisfaction variableindicated that the midwiveshave maximized the utilizationof SICANTIK application. However, most of the health workerswere not ready to use SICANTIK health information system in the community health centers.