Online ISSN: 2515-8260

EVALUATION OF SERUM LIPID PROFILE IN CHILDREN WITH NEPHROTIC SYNDROME: A PROSPECTIVE COHORT STUDY FROM NORTH INDIA

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1Deepali Bangalia, 2 Satyendr Sonkariya, 3Chethan C.S., 4Laxman Singh Charan, 5Anil Kumar Jain

Abstract

Background: Nephrotic syndrome is a collection of clinical findings due to kidney damage. This includes protein in urine, low blood albumin levels, high blood lipids, and significant edema. The main cause of hyperlipidemia in patients with NS is probably increased hepatic lipogenesis, a non-specific reaction to falling oncotic pressure secondary to hypoalbuminemia. Hyperlipidemia is usually observed during the active phase of the disease and disappears with resolution of proteinuria. However, it may persist in some cases, leading to increased risk of atherosclerosis in later life and development of progressive renal injury. The current study was carried out to evaluate dyslipidemia in children with nephrotic syndrome.

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