Background: There is a rising trend in diabetes in our country. Diabetes leads to several micro and macro vascular complications, of which peripheral arterial disease can worsen the prognosis of diabetic foot patients. Most of the patients tend to be asymptomatic. Finding a non-invasive and accessible screening test for early detection and treatment of diabetic foot complications is important. The aim of this study was to compare pulse oximetry and ankle brachial pressure index (ABPI) to doppler scan as a reference standard to assess their usefulness in detecting peripheral arterial disease and to asses if they are acceptable screening tool to detect hemodynamically significant lower extremity arterial occlusive disease