ABSTRACT Introduction: Pneumothorax occur most during neonatal age than other age of life in human being, this more related to high morbidity and death rate. It started form damage to alveoli that more distended. The air seepages lengthways of the perivascular sheath of connective tissue inside to the pleural space, The aim of our study is to assessment of prevalence, recognize the danger factors and to define the clinical features, treatment and consequence of neonates that have pneumothorax and determine the fate of neonates after treatments. Method: Prospectively collected data from newborn infants with pneumothorax observed and treated at the Neonatal Intensive Care Unit (NICU) in al immamian alkadhomain medical city, Sociodemographic data of neonates, clinical features of pneumothorax and treatment of pneumothorax. Finally, assessment the fate of neonate assessed. Results: A cross section descriptive study on 41 neonates mean age (34.6 ± 3) weeks most age group 31 – 40 weeks 85% and weight (2 ± 0.7) kg most neonates (49%) with 2.1 – 3 kg, 34% females and 66% males, 61% of neonates are single parity, 71% of neonates not need to antenatal steroid, while 56% of neonates delivered by CS, 71% of neonates with Apgar score less than 7 in first 1 min., Significant association between sociodemographic variables and clinical features as show in table 4; 52% of right pneumothorax occur in male, 88% of left pneumothorax occur in male and 100% of bilateral pneumothorax occur in male. 57% of RDS occur females while 43% of RDS in male. 100% of TTN occur in single parity. 67% of pneumonia occur at age group 21- 30 week. Significant association between sociodemographic variables and treatment and fate as show in table 5; 56% of neonate’s need C-pap were females and 44% were males. 56% of neonates need O2 therapy with weight 2.1-3kg, 26% of them that need O2 therapy with weight 1-2 kg. 55% of alive neonates are males and 45% are females, 72% of single parity neonates still alive. Conclusion: Pneumothorax is moderately common in the NICU. The fate of neonates are 71% still alive and 29% dead. Pneumothorax itself was not a factor of death, probably due to the sufficient and rapid therapy used in the NICU.