Background: The endometrium which linesthe uterine cavity is one of most dynamic tissues in the human body. The endometrial sampling is chosen to evaluate abnormal uterine bleeding. Chronic endometritis is considered as an infectious or a reactive process Materials and Methods: It is a prospective study done for period of 2 years in Department of Pathology, Government Maternity Hospital, Hyderabad. Sample size was 50. All cases of Abnormal Uterine Bleeding in Reproductive age group were chosen and their endometrial curettage samples were processed, histopathological & immunohistochemicalstudy was done. The results obtained were tabulated&assessed statistically.