Background:The present study was undertaken for comparing the impact of desensitizing agents on the retention of crowns cemented with luting agents.Materials & methods:20 freshly extracted mandibular molar teeth were selected. Storing of the tooth specimens in the normal saline was done followed by thorough cleaning. All the specimens were divided into two study groups as follows: Group 1: Glass ionomer cement (Control), and Group 2: Glass ionomer cement (GC Tooth Mousse desensitizer). Crowns were fabricated and were subjected under universal force testing machine. All the results were recorded in Microsoft excel sheet and were analyzed by SPSS software.Results:Among the group 1, mean tensile bond strength was 45.9 Kg while in the group 2, mean tensile strength was 44.2 Kg respectively. While comparing statistically, non-significant results were obtained.Conclusion:Application of desensitizing agents might be designated during fabrication of crowns as it will not affect the retentive ability of the luting cements.