Background: Cardiovascular disease (CVD) is the major reason of mortality among noncommunicable diseases (NCDs), constituting 26% in India. The present study was conducted to evaluate drug utilization in cardiovascular disease. Material and methods: The prospective observational study was conducted for a period of 6 months to evaluate drug utilization in cardiovascular disease. The study included a total of 600 patients admitted to intensive coronary care unit. All the medical prescriptions were collected and the data was used to analyze the prescription pattern by prescribing indicators and individual drug use by DDD measure. The data was collected and analyzed for counts and percentages. The mean and standard deviation was computed for continuous variables.