OBJECTIVE  To assess the effectiveness of Triple test (TT) in evaluation of breast diseases.  To compare Triple Test (as a combined diagnostic modality) to each of its components.  To find whether addition of Ultrasound to Triple Test, provides any benefit to the diagnosis STUDY DESIGN Prospective study SETTING Krishna Hospital and Research Centre , Karad SUBJECTS AND METHODS All patients fulfilling inclusion criteria with Breast disease who visited surgery OPD in Krishna Hospital & Medical Research Centre, Karad within the duration of December 2020 to July 2022, were assessed based on the guidelines of triple test for breast diseases along with USG of affected breast. The final result was obtained and the accuracy of all the tests were compared.