Online ISSN: 2515-8260

Evaluation of Antibacterial Property of Medicinal Liquid Soap having JusticiaadhatodaL.(Adhatoda)Leaf Extracts

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KulBhaskar

Abstract

INTRODUCTION Soaps are the products of basics aponificationreactions (Chukwulozie, 2014). Theyare in useamong society from its discovery by the ancientBabylonians as acleansing material(Warra,2010).Currently,therearealarge numberofcommercially available medicinal soapswhich come mainly as solid bar or liquid soaps. The difference between solid and liquid soaps isthatinsolidsoapNaOH is used as base,whereas in liquid soapsKOH is used as base in there preparation (Chukwulozie,2014). Different types of naturalingredients are used to enrich the soaps medicinalpropertieslikeantiviral, antibacterial,antifungal,antioxidant,anti-inflammatoryetc.tothefinalproduct(Kole,2005).Besides these, manynaturalingredientsare also used to improvethecolor,textureandodorofthesoapproducts.During preparation of medicinal soap products, it is most importantanddesirable alsotousenaturalingradients instead of harmfulsyntheticchemicals,toobtainthedesired bioactivities. Both BHT (2,6-ditert-butyl-4-methylphenol)and Triclosanareexamplesofsyntheticcompoundswhichhavebeenmostly used in such consumer soap products to giveantioxidant and antibacterial properties respectively.However,these synthetic substances could be replaced bynaturalingredientsobtainedfromcommonmedicinalplants. Turmeric, sandalwood, neem, jasmine and lemonessencearesome ofthemostcommoningredients usedindifferent skincareproductsincludingmedicinal soaps (Kole, 2005). In present study,effortsweremadetopreparemedicinalsoapproductsby usingbiologically activeleafextractsofJusticiaadhatoda L. JusticiaadhatodaL.is an evergreen shrub, whichusuallygrowswellinlowmoistureareasanddry soils to a height of 2-3 meters. Its leaves aresimple, opposite, large and lance shaped. TheplantisnativetoIndian subcontinent andare distributed incountrieslikeSriLanka,India,NepalandPakistan(Sampath,2010).JusticiaadhatodaL.contains a varietyofalkaloids, saponins, flavonoids, tannins and phenolics. Quinazolinealkaloid ,vasicine is an impotant constituent of it.Lycopenes,ascorbicacidetc are the other important compounds present here.(Wankhede,2015).

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