Background: Bronchoscopy is one of the most commonly performed safe procedures worldwide by pulmonologists for diagnostic and therapeutic purposes. It has a few complications such as bleeding, bronchospasm, laryngospasm, iatrogenic infections, atelectasis, and pneumothorax. The incidence of bleeding is low and rarely life-threatening, with a mortality rate of 0-0.04%. The greatest danger in a bleeding situation is aspiration and blood flooding of the alveoli (1,2). Cold saline is now regularly used to reduce bleeding during bronchoscopic operations, and other drugs such as adrenaline and terlipressin have also been employed. but either connected with difficulties or a scarcity of research (9,10). As a result, this study was conducted since there have been few studies on tranexamic acid, which requires greater assessment in terms of efficacy and safety. As a result, we conducted this study to evaluate the effectiveness and safety of tranexamic acid endobronchial instillation