Pharmacotherapy is defined as a treatment procedure for a specific health condition by using pharmaceutical products as medicine and developing a drug dependency with the help of legal prescribing institutions. This process helps to maintain the functional capacity of patients and reduce the cost of treatment procedures in depression treatment efficiently. This factor helps to identify the way meditation is used for treatment and to prevent mental disease with the help of effective drugs. The treatment procedure follows strategic treatment through the application of antidepressants for continuation and maintenance in resolving depressionrelated problems among patients. Pharmacotherapy of depression helps to provide a compressive review of anti-depression therapy that is used in the clinical process and constructed sessions with therapists and counsellors appropriately. The main goal of depression treatment is to achieve dimension and restore the functionality of the individual and develop the quality of mental health efficiently.The aim of the study is to recognize the impact of different types of antidepressants on the health condition of individual patients and identify the root cause of depression among the individuals. Pharmacotherapy guides patients to achieve remission from the symptoms and restore their baseline of psychological functions with the help of clinical administrative depression treatment.