The object of the study were 97 patients, children with community-acquired pneumonia associated with mycoplasma and chlamydial infection aged from 1 to 7 years. Dynamic analysis has proven the benefit of differentiated treatment. In group II, during therapy on the 6th day from the start of treatment, a pronounced positive dynamics of physical data was observed. Analysis of the effect of differentiated treatment on the parameters of biochemical data of the examined patients revealed a positive effect on the studied parameters. There was a significant decrease in the content of NO2(NO3), HP, ONOO- and a significant increase in eNOS compared with the data of group I. After treatment, the concentration of MDA was 1.8 times higher than in practically healthy children and 1.4 times lower than in children who received basic therapy. A decrease in the level of MDA in the blood in patients with CAP associated with MI and CI during treatment states a decrease in free radicals and an increase in the intensity of AOS.