This study was designed to evaluate the effect of Lycopene powder and /or vitamins AD3Eadding to growing Awassi Male Lambs on bloodphysiologicalTraits. Twenty healthy Awassi Male Lambs were selected for this study at approximately (4-5) month of age and average body weight (BW) of 19 kg and were reared in the livestock farm, experimental feeding was continued from 3/12/2019 to 2/3/2020 in addition to 15 day as adaptation period. After adaptation period, lambs were randomly divided into four groups (5 lambs/group), The first group used as a control with no treatment, the second group received orally a solution of mixed vitamins (AD3E) (A 20.000 IU, vitamin D3 10.000 IU and vitamin E 60 mg /lamb) biweekly, the third group, usedLycopene powder, (1% of theconcentrate diet) and same dose of (AD3E) and the fourth group, usedLycopene powder (1% of theconcentrate diet). However, all groups were fed a concentrate diet (2.5%DM of live body weight) in addition to alfalfahay (1 kg / head/day . Bloodsamples were collected from jugular vein monthly for blood parameters measurement include: hemoglobin (Hb), packed cell volume (PCV),totalserumprotein(TSP),Albumineand Globulinewere determined.