Abstract: Our results show that the pesticides butylcaptax, dropp and karate are highly toxic pesticides, when exposed to these pesticides, the activity of the enzyme of the P-450 monooxygenase system is disrupted. Also, the research results showed that when poisoning with the above pesticides, ultrastructural, and therefore functional changes in the subcellular components of embryonic hepatocytes occur. When using RAF (plant antioxidant factor), enzyme activity and other indicators are significantly restored, which indicates that RAF has antioxidant properties.